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Abstracto:

Abstract

BACKGROUND:

Vertebroplasty (VP) and kyphoplasty (KP) are two minimally invasive techniques used to relieve pain and restore stability in metastatic spinal disease. However, most of these procedures are performed in the thoracolumbar spine, and there is limited data on outcomes after VP/KP for cervical metastases. The purpose of this article is to evaluate the safety and efficacy of VP and KP for treating pain in patients with cervical spine metastases.

Int J Spine Surg.


Abstracto:

Abstract

Meningiomas are among the most common intracranial tumors. The treatment of choice for these lesions is complete resection, but in 50% of cases it is not achieved due to tumor location and/or surgical morbidities. Moreover, benign meningiomas have high recurrence rates of up to 32% in long-term follow-up. Molecular analyses have begun to uncover the genetics behind meningiomas, giving rise to potential genetics-based treatments, including gene therapy. The authors performed a literature review on the most relevant genes associated with meningiomas and both current and potential gene therapy strategies to treat these tumors. Wild-type NF2 gene insertion, oncolytic viruses, and transfer of silencing RNA have all shown promising results both in vitro and in mice. These strategies have decreased meningioma cell growth, proliferation, and angiogenesis. However, no clinical trial has been done to date. Future research and trials in gene insertion, selective inhibition of oncogenes, and the use of oncolytic viruses, among other potential treatment approaches, may shape the future of meningioma management.

Neurosurg Focus.


Abstracto:

RESUMEN

Los cordomas son neoplasias de lento crecimiento de la línea media. Representan aproximadamente 1% de los tumores

malignos de hueso. Corresponden de 0.1 a 0.2% de las neoplasias intracraneales. De origen embrionario notocordal, inician su

sintomatología entre la tercera y quinta década de la vida, con una media diagnóstica de 43 años. Se presentan como una lesión

de masa en la región clival, con destrucción de esta y con extensión a nasofaringe. El diagnóstico definitivo es histopatológico.

La supervivencia de los pacientes no tratados se estima en una media de 28 meses después del inicio de la sintomatología,

posterior a la terapia de radiación o quirúrgica es de 6.6 años y 3.6 años respectivamente. La quimioterapia no ha comprobado

beneficio, aun así su uso está justificado en pacientes jóvenes, suponiendo que esto detuviera el crecimiento tumoral y una vez

alcanzada cierta edad se indicaría la radioterapia. Hay limitaciones con lo que respecta al tratamiento, aun con los avances en

cuanto a estudios de imagen y técnicas de resección quirúrgica.

Palabras clave: Cordoma, neoplasia disontogénica, notocordal.

Rev Mex Neuroci


Abstracto:

ABSTRACT

Microsurgical landmarks of the facet joint complex were defined to provide guidance and security within the tubular retractor during transforaminal surgery. A retrospective observational study was performed in segments L4-L5 by the left side approach. Microsurgical relevant photos, anatomical models and drawing were used to expose the suggested landmarks. The MI-TLIF technique has advantages compared with conventional open TLIF technique, however minimally invasive technique implies lack of security for the surgeon due to the lack of defined microanatomical landmarks compared to open spine surgery, and disorientation within the tubular retractor, the reason why to have precise microsurgical references and its recognition within the surgical field provide speed and safety when performing minimally invasive technique.

Keywords: Spinal fusion; Arthrodesis; Lumbar vertebrae; Anatomic landmarks.

Coluna/Columna


Abstracto:

Abstract

Various minimally invasive techniques have been reported as an alternative to conventional lumbar decompression. The major advantage of these minimally invasive procedures lies in their reduction of unnecessary exposure and tissue trauma. Our objective was to describe a minimally invasive procedure for lumbar spinal stenosis decompression by enlarging the lumbar interspinous space, approaching it with a tubular retractor, and assisting with microscopy. Thoracolumbar fascia and paravertebral muscles are preserved throughout the whole procedure. Iatrogenic instability of the spine can be avoided if during the procedure both joints are just undercut in order to decompress the subarticular space. The approach described in this manuscript could be used as an alternate minimally invasive surgical procedure for the treatment of central and lateral lumbar spinal stenosis.

KEYWORDS:

Spinal stenosis; lumbar region; minimal access; minimally invasive; spine surgery; surgical decompression.

J Spine Surg


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